Uterine Artery Ligation to Decrease Blood Loss With Central Placenta Previa

Minia Maternity University Hospital

Status: Completed

Conditions: Placenta Previa Without Hemorrhage

Treatments: Procedure: Uterine artery ligation

Study type: Interventional

Funder types: Other

Identifiers

NCT02002026

U1111-1150-4666

Details and patient eligibility

About

This trial will address the effect of uterine artery ligation during Cesarean section in cases with placenta previa to decrease blood loss.

Full description

This Study will address the effect of uterine artery ligation prior to fetal delivery during Cesarean section in cases with central placenta previa to guard against postpartum hemorrhage and to minimize blood loss.

Enrollment: 52 patients

Sex: Female

Ages: 18 to 49 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Placenta previa is diagnosed when the lowest placental edge is located within 5 cm of the internal os at ultrasound
• Symptomatic Placenta previa with at least one episode of bleeding
• Estimated gestational age within 28 to 40 weeks
• Maternal age > 18 years
• Informed consent
• Social affiliation

Exclusion criteria

• Premature rupture of membranes
• Severe bleeding.
• Abnormal fetal heart rates.
• Pre-eclampsia, chorioamnionitis, severe chronic renal disease.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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52 participants in 2 patient groups, including a placebo group

Ligation group

Active Comparator group

Description:

Uterine artery ligation will be done for patients in this group

Treatment:

Procedure: Uterine artery ligation

Control group

Placebo Comparator group

Description:

Conventional CS

Treatment:

Procedure: Uterine artery ligation