Uterine Cavity and Blood Flow After Conservative Management of Placenta Previa/Accreta

Assiut University

Status: Completed

Conditions: Improving Quality of Life

Treatments: Device: Doppler

Study type: Observational

Funder types: Other

Identifiers

NCT02878187

PP

Details and patient eligibility

About

Bleeding is the most significant cause of maternal death worldwide with more than half of those occurring within the first day of delivery. About 10.5% (some estimate as high at 12-17%) of live births world-wide, or about 14 million births, are complicated by postpartum hemorrhage; a woman dies every 4 minutes from postpartum hemorrhage. Uterine atony and placenta accreta are the two leading causes of postpartum hysterectomies with up to 64% of Cesarean hysterectomies done for abnormally adherent placentation

Full description

No previous studies performed for evaluation of the effect of those procedures on the uterine cavity or uterine blood flow. Most of the studies in the literature evaluated the menstrual and fertility outcome after conservative measures for intraoperative hemorrhage due to placenta previa/accreta were retrospective and depend on the resumption of menses and pregnancy rate

Enrollment: 100 patients

Sex: Female

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Women Age 18-40 years
2. Gestational age of pregnancy 28-40 weeks
3. Diagnosed antenatally as placenta previa/accreta
4. Patients who will be managed by conservative surgical techniques for intraoperative hemorrhage
5. Women who will accept to participate in the study and are reliable for follow-up

Exclusion criteria

• 1- Patients who will be managed by hysterectomy 2- Patients who will be managed by conservative leaving the placenta in-situ 3- Diabetic or hypertensive women 4- Women who will refuse to participate in the study

Trial design

100 participants in 2 patient groups

placenta previa

Description:

all women managed by conservative surgical techniques during cesarean section after intraoperative hemorrhage due to placenta previa/accreta

Treatment:

Device: Doppler

healthy controls

Description:

women delivered by Cesarean for any other indication with no intraoperative hemorrhage or any additional surgical techniques performed during Cesarean

Treatment:

Device: Doppler