Uterus Transplantation From Live Donor (utx)

Sahlgrenska University Hospital

Status: Completed

Conditions: Primary Uterine Infertility

Treatments: Procedure: uterine transplantation

Study type: Interventional

Funder types: Other

Identifiers

NCT01844362

utx-ld

Details and patient eligibility

About

Uterus transplantation, as a possible future treatment for uterine factor infertility, has been developed in animal species during the last decade.

The study protocol includes transplantation of the uterus from a live donor (mother, relative, friend) into women with absolute uterine factor infertility (lack of uterus from birth or due to life saving hysterectomy).The recipient will be treated by standard immunosuppression and transfer of embryos (acquired by IVF before surgery) will be attempted when at least 12 months have passed from transplantation. Approval for a case series including up to 10 patients has been acquired.

Full description

The study is ongoing, with inclusion of 9 patients.

Enrollment: 9 patients

Sex: Female

Ages: 18 to 39 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• less than 39 years
• good general health

Exclusion criteria

• poor ovarian resaerve or older than 39 years
• systemic or psychiatric disease

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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9 participants in 1 patient group

Uterine transplantation

Experimental group

Description:

Patients undergo transplantation of the uterus from live donor.

Treatment:

Procedure: uterine transplantation