Utility of Renal Biomarkers in Cirrhosis

University Hospitals (UH)

Status: Completed

Conditions: Cirrhosis; Ascitis

Study type: Observational

Funder types: Other

Identifiers

NCT01217983

PRD 2010-I-15 (Other Grant/Funding Number)

10-056 Med 10-019

Details and patient eligibility

About

Evaluation of kidney function is critical in cirrhotic patients as there is a clear relationship between renal failure and prognosis. The investigators hypothesized that in this population new biomarkers of renal function could help in early detection of acute renal failure and in discrimination between renal and pre-renal causes. Finally the investigators hypothesized that such biomarkers could predict short-term outcome in this population.

Enrollment: 105 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥ 18 years
• Known or suspected cirrhosis
• Suspected ascitis
• Informed consent signed

Exclusion criteria

• Proven multifocal hepatocellular carcinoma
• Acute gastric hemorrhage (active or < 2 weeks)
• Known end-stage renal disease or on dialysis before admission
• Recipients of kidney or liver transplants
• Transferred from another institution