Utility of Whole-body MRI in the Detection of Traumatic Injuries of Undetermined Origin in Children (PEDIMA)

Rennes University Hospital

Status: Completed

Conditions: Traumatic Injuries

Treatments: Other: diagnostic whole body MRI

Study type: Interventional

Funder types: Other

Identifiers

NCT01743703

2011-A00393-38

Details and patient eligibility

About

The diagnosis of abuse in children relies heavily on the presence of skeletal and extraskeletal injuries. However, some lesions are not seen by initial skeletal survey. And the investigators have to complete the skeletal survey with either bone-scan or CT scan or whole-body MRI. whole-body MRI has proved its worth in the pediatric population for the evaluation of skeletal and extraskeletal lesions in children with cancer or infectious diseases. Thus, whole-body MRI would allowed to have total picture of children without ionising radiation exposure.

Enrollment: 199 patients

Sex: All

Ages: Under 3 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Infant hospitalised for sub-dural hematoma or skeletal injuries due to non accidental traumatism or skin lesions or abdominal injuries of undetermined origin

Exclusion criteria

• Sub-dural hematoma of accidental origin or skeletal injuries of accidental
• Origin or known origin of lesions.
• Subject already included in the study

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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199 participants in 1 patient group

whole body MRI

Other group

Description:

diagnostic whole body MRI, and skeletal imaging following guidelines (whole body radiographic and scintigraphic screening)

Treatment:

Other: diagnostic whole body MRI