Utilizing Augmented Reality as an Adjunct for Smoking Cessation

H. Lee Moffitt Cancer Center and Research Institute

Status: Completed

Conditions: Smoking

Treatments: Behavioral: Augmented Reality 4; Behavioral: Augmented Reality 2; Behavioral: Augmented Reality 3; Behavioral: Augmented Reality 1

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT04101422

MCC-20007

R34DA047598-03 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The purpose of the study is to develop an preliminary test a tobacco smoking-related augmented reality (AR) paradigm for eventual development as an adjunctive tobacco cessation intervention.

Enrollment: 197 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Currently smoking ≥ 3 cigarettes per day for the past year
• Breath carbon monoxide (CO) level ≥ 5 ppm
• Motivated to quit smoking
• Aim 1 & 2 Only: Valid home address in the Tampa Bay area
• Functioning telephone number
• Can speak, read, and write in English
• Aim 3: Must have a smartphone that participant is willing to use during the study
• Aim 3: Motivated to quit smoking within the next month

Exclusion criteria

• Regular use (e.g., no more than 1/3 of month) of other tobacco products (cigars)
• Household member already enrolled in the study

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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197 participants in 5 patient groups

Development of Augmented Reality (AR) Application

No Intervention group

Description:

Investigators will collaborate with an AR software specialist to develop AR stimuli that are embedded within a basic digital application.

Pilot Testing of AR Application

Experimental group

Description:

AR stimuli (smoking, e.g, cigarette, ashtray, lighter; and non-smoking, e.g., pen, notebook, eraser) will be piloted on a small group of smokers to receive feedback and modify as needed. Participants will answer questions from a 10 point Likert scale that will asses urge from 1 (absolutely no urge to smoke) to 10 (strongest urge to smoke) and reality/co-existence (how realistic the item looks, and it's integration into the environment), from 1 (Not at all) to 10 (Very Much). Participants will then be asked additional open-ended questions about the quality of the images following the ratings of the images.

Treatment:

Behavioral: Augmented Reality 1

Laboratory Validation of AR Stimuli Session 1: Cue Reactivity

Experimental group

Description:

Participants will attend 1st lab based session that will test cue-reactivity. Participant will be randomized to view either AR images, or in vivo items first. Order of presentation of items will also be randomized within the type (AR or in vivo).Session 1 should last under 1 hour.

Treatment:

Behavioral: Augmented Reality 2

Laboratory Validation of AR Stimuli Session 2: Extinction

Experimental group

Description:

Participants will be randomized into either the extinction or control group. 28 trials of AR cues will be presented for each group. Both groups will receive the same neutral cue in Trial 1 (to establish baseline urge) and the same smoking cue in Trial 2 (for pre-test cue-reactivity). The extinction group will receive smoking cues for trials 3-26, whereas the control group will receive neutral cues. Both groups will receive matched smoking cues for trial (27) followed by matched neutral cues for the final trial (28), for post-test cuereactivity. Each cue will be presented for 1 minute and will be shown 4 times in trials 3-26. Following each cue, participants will complete the single-item measure of urge. Following the final trial (28) for both groups, participants will be presented with one of their own cigarettes and asked to take at least one puff. Latency to smoke will later be determined using time stamps on the video recording. Session 2 is expected to last 1.25 hours.

Treatment:

Behavioral: Augmented Reality 4

Testing AR Application

Experimental group

Description:

Participants will be instructed to use the AR app that presents smoking-related stimuli (cigarette, ashtray, lighter) in locations/situations where they typically smoke with the goal of at least 5 uses per day for 7 days. Usage and rating data will be collected in real-time. Participants will also be asked to rate their urge to smoke on the smartphone app at selected times. Participants will complete a telephone interview to provide additional feedback on the app, answer questions related to smoking behavior, and receive an in-person interview on their perceptions of the app as a potential cessation tool. Participants will use the smart phone application for 7 days.

Treatment:

Behavioral: Augmented Reality 3