Utilizing GI: Exploring an Optimum Glycaemic Profile for Cognitive Function Across the Day

Matthew Grout

Status: Completed

Conditions: Mood; Cognitive Performance; Glucose, High Blood; Glucose, Low Blood

Treatments: Dietary Supplement: Low Glycaemic Diet; Dietary Supplement: High Glycaemic Diet

Study type: Interventional

Funder types: Other

Identifiers

NCT03346746

2016-206-DL

Details and patient eligibility

About

This study provides participants with two diets that vary in their glycaemic index values (low vs. high), whilst also measuring cognitive performance and mood.

Full description

Therefore, the current study introduces cognitive testing into study procedures. Participants will consume the favourable and unfavourable conditions (each containing three meals) on separate days following a crossover, randomised, couterbalanced design. The primary dependent variable is cognitive function, whilst secondary measures include glucose and mood. It is hypothesised that the favourable meal profile will be associated with cognitive and physiological benefits relative to the unfavourable meal profile.

Enrollment: 40 patients

Sex: All

Ages: 18 to 25 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Aged between 18 and 25 years of age
• Willing to participate in the entire study (signed informed consent required)
• Male or female (not pregnant)

Exclusion criteria

• Suffer from diabetes

• Are anaemic

• Smoker

• Have any food intolerances or allergies

• History of alcohol or drug misuse

• Diagnosed with any of the following;

  • High blood cholesterol
  • High blood pressure
  • Thyroid disorder
  • Heart problems, stroke or any vascular disease in the past 12 months
  • Inflammatory diseases such as rheumatoid arthritis
  • Bone related conditions, such as osteoporosis
  • Renal, gastrointestinal, respiratory, liver disease or cancer

• You are presently taking part in another clinical trial or research study

• You are an elite athlete (very high intensity training more than 3 times a week)

• You are currently on a specific diet, and are unwilling to cease during the testing period

• You are intending to regularly use medication which affects gastrointestinal motility

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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40 participants in 2 patient groups

Low GI diet

Experimental group

Description:

This diet contained three Low GI meals. This was the Low Glycaemic Diet intervention.

Treatment:

Dietary Supplement: Low Glycaemic Diet

High GI diet

Experimental group

Description:

This diet contained three meals, all with a high GI value. This was the High Glycaemic Diet intervention.

Treatment:

Dietary Supplement: High Glycaemic Diet