Utrecht COhort for Lung Cancer Outcome Reporting and Trial Inclusion (U-COLOR)

UMC Utrecht

Status: Active, not recruiting

Conditions: Lung Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT05069792

NL71047.041.19

Details and patient eligibility

About

Objective: 1) To collect information on patient characteristics, short- and long-term clinical and patient-reported outcomes; and 2) to create an infrastructure for efficient, fast, and pragmatic randomized evaluation of new interventions.

Study design: Observational, prospective cohort study, according to the 'TwiCs' design.

Study population: All patients with lung cancer referred to the Department of Pulmonology or the Department of Radiotherapy of the UMC Utrecht.

Main study parameters/endpoints: Clinical parameters (performance status, co-morbidity, oncological history, symptoms, imaging, technical and treatment data), clinical endpoints (toxicity, reintervention and survival), and patient-reported outcomes.

Full description

The prospective U-COLOR cohort (Utrecht COhort for Lung cancer Outcome Reporting and trial inclusion), aims to:

• Gather data on natural disease progression, treatment response, disease recurrence, complications, quality of life and survival of patients with lung cancer;
• Collect a patient group willing to participate in studies;
• Facilitate multiple, parallel randomized controlled trials within the cohort.

Enrollment: 2,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥ 18 years;
• Radiographic and/or histologic proof of lung cancer;
• Referred to Department of Pulmonology or the Department of Radiotherapy for treatment.

Exclusion criteria

• Mental disorder or cognitive dysfunction that hinders the patient's ability to understand the informed consent procedure and/or study details;
• Patients with severe psychiatric disorders;
• Inability to understand the Dutch language.