Vaccination Against SARS-Cov2 (COVID-19) in Chronic Inflammatory Rheumatism and Factors Determining Its Decision. (VACCI-RIC)

Hopital Nord Franche-Comte

Status: Completed

Conditions: Spondyloarthritis; Rheumatoid Arthritis

Treatments: Other: Non intervention

Study type: Observational

Funder types: Other

Identifiers

NCT04970550

2021-A01013-38

Details and patient eligibility

About

Rheumatoid arthritis and spondyloarthritis (ankylosing spondylitis and psoriatic arthritis mainly) are chronic inflammatory rheumatism (RIC), frequently onset in young adults. The prevalence is respectively 0.3 to 0.8% and 0.4%. or about 600,000 people. The "basic" treatments (DMARDs), essential to control the progression of the disease, are classified into csDMARDs (chemical), the first of which is methotrexate, or bDMARDs (biological). These treatments are immunomodulators and there is an increased risk of severe infection under these therapies. Several vaccinations are therefore recommended by learned societies in patients receiving these treatments, in order to prevent certain infectious risks.In the current pandemic context, the vaccination of these patients against SARS-Cov2 is a major issue in their management and is recommended by the French society of rheumatology. However, many patients express doubts about this vaccination or refuse it. The factors associated with the vaccination will are not known. Better identifying them would make it possible to adapt the information to be given to our patients to promote their adherence.

Enrollment: 150 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Ambulatory patients
• Men or women of any age
• Follow-ups for chronic inflammatory rheumatism such as rheumatoid arthritis or spondyloarthritis
• Treated with methotrexate or biotherapy.

Exclusion criteria

• Patients not treated with biotherapy or methotrexate.
• Patients in whom the assessment could not be performed reliably