Vaccine Confidence Study Among Historically Marginalized Racial and Ethnic Groups

Boston Medical Center (BMC)

Status: Enrolling

Conditions: Vaccine Refusal; Vaccine Hesitancy

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT06639386

H-44825

Details and patient eligibility

About

Achieving optimal vaccination rates is vital for protecting the health and well-being of all individuals. This specific study focuses on the MMR and RSV vaccines in pregnancy and early childhood, which have been shown to reduce RSV and MMR-related illnesses, hospitalizations, and deaths. Efforts to improve vaccination rates have not been equally effective across the entire population; this has resulted in poorer outcomes from interventions for certain populations who are vaccine-hesitant.

This study seeks to understand how to best increase vaccine confidence in marginalized populations. To do this, the investigators will interview parents of children who receive care at Boston Medical Center (BMC), Community Health Workers and other Clinical providers at BMC, leading experts in the fields of vaccine confidence and implementation science, and key public health stakeholders/officials.

Enrollment: 80 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Parent and child-

• The birthing parent of any age of a child (aged 12-24 months) who receives primary care at Boston Medical Center
• A birthing parent who is registered as a patient at Boston Medical Center
• The birthing parent must have been pregnant between the months of October and February (RSV season)
• The birthing parent must be comfortable completing an interview in English, Spanish, or Haitian Creole.

Clinician

• Clinical provider (including Community Health Workers, Physicians, Physician Assistants and Nurse Practitioners) aged 18+ years at Boston Medical Center within Pediatrics, Family Medicine, or OB/GYN. These clinicians will have been involved in past or current successful vaccine-specific Evidence Based Interventions (EBI) beyond BMC and its affiliated Community Health Center (CHC).

EBI Expert

• Content experts (aged 18+ years) in the areas of Implementation Science, Vaccine-specific EBIs, and Prenatal genetic counseling

Exclusion criteria

• Clinical provider (including Community Health Workers, Physicians, Physician Assistants and Nurse Practitioners) at NON-BMC clinic/Community Health Center
• Content experts - NON-Vaccine evidence based interventions (EBIs)

Trial design

80 participants in 3 patient groups

Parents of children 12-24 months

Description:

30 birthing parents and their 12-24 month old infants will be enrolled into the study. Study activities (enrollment and interviews) can be conducted with participants in English, Haitian Creole, or Spanish.

Clinicians

Description:

35 clinicians at BMC will be recruited to participate in anonymous, one-time interviews. The sample will include 20 Community Health Workers, 10 pediatric/family Medicine clinicians, and 5 Obstetricians. Recruitment will focus on clinicians who have a history of successful vaccine-specific Evidence-Based Interventions (EBIs) beyond BMC and its affiliated CHCs.

Evidence Based Intervention (EBI) Experts

Description:

15 EBI Experts will be identified from a literature review of published peer-review articles in the fields of vaccine EBIs, implementation science, and prenatal genetic counseling.