Vacuum-Assisted Dressings (V-AD) in the Management of Open Chest Wounds

Mayo Clinic

Status: Completed

Conditions: Open Chest Wounds

Treatments: Device: Wound Vacuum-assisted dressing; Other: Control group

Study type: Interventional

Funder types: Other

Identifiers

NCT02803164

16-002486

Details and patient eligibility

About

Vacuum-assisted dressings (V-AD) are effective in treating patients with open chest wounds (OCW) and will decrease the time-to-closure of such wounds when compared to a historical cohort of patients managed by traditional wound care management.

Enrollment: 21 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Subject is scheduled to undergo surgical intervention(s) as part of the standard care for management of intra-thoracic infection.

Exclusion criteria

• Patent bronchopleural fistulas. Severe respiratory failure requiring mechanical ventilation at the time of first consultation.
• Proven or suspected malignancy in the wound. Coagulopathy due to medical or pharmacologic reasons. Dependency on anticoagulants or antiplatelet medication due to high risk for adverse events if these medications are stopped for a prolonged period of time.

Allergy to acrylic products.

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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21 participants in 2 patient groups

Vacuum-assisted dressing

Other group

Description:

Eligible subjects will receive negative pressure wound therapy during surgery.

Treatment:

Device: Wound Vacuum-assisted dressing

Historical control group for comparison

Other group

Description:

Retrospective review of subjects medical records with open chest wounds who were treated with the traditional treatment techniques.

Treatment:

Other: Control group