Vaginal Microbiota Among Postmenopausal Women

Lawson Health Research Institute

Status: Completed

Conditions: Vulvovaginal Atrophy

Study type: Observational

Funder types: Other

Identifiers

NCT01084616

R-09-804

16182E (Other Identifier)

Details and patient eligibility

About

It is known that vaginal bacteria have an impact upon the health status of the host, in some cases protecting against infection and in other cases causing infection, depending on the bacterial types present. This study will compare the composition of vaginal bacteria to symptoms of vaginal dryness in order to try and identify if certain bacteria might cause some of the problems associated with vaginal dryness among post-menopausal women.

Enrollment: 16 patients

Sex: Female

Ages: 30 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Between 30 and 80 years old.
• Postmenopausal = 12 months of spontaneous amenorrhea or 6 months of spontaneous amenorrhea with serum FSH levels > 40 mIU/ml or 6 weeks postsurgical bilateral oophorectomy with or without hysterectomy.
• Prepared not to take hormone replacement therapy during 8 weeks follow-up and not taking estrogen alone or estrogen/progestin containing drug products at the time of screening.

Trial design

16 participants in 2 patient groups

Vaginal Dryness

Non-vaginal dryness