Validating a Clinical Decision Support Tool for Stratifying Stroke Risk for Dizziness/Vertigo

Chiayi Christian Hospital

Status

Not yet enrolling

Conditions

Vertigo

Dizziness

Treatments

Radiation: Magnetic resonance imaging

Study type

Observational

Funder types

Other

Other U.S. Federal agency

Identifiers

NCT06010550

IRB2023009

Details and patient eligibility

About

This study aims to validate a machine learning model that stratifies the risk of stroke in patients who present to the emergency department with dizziness or vertigo.

Full description

This is a cross-sectional, hospital-based study, with no randomization procedure. Over a 21-month period, approximately 600 subjects will be enrolled. The study will assess the risk of stroke in each patient using a machine-learning model. To detect ischemic or hemorrhagic stroke, each patient will undergo a non-contrast brain magnetic resonance imaging study. The predictive performance of the machine-learning model will be evaluated in terms of accuracy, precision, recall, F1 score, and area under the receiver operating characteristics curve.

Enrollment

600 estimated patients

Sex

All

Ages

20+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Presenting to the emergency department with dizziness or vertigo
Aged ≥ 20
Dizziness or vertigo lasting for at least 1 hour and < 7 days
Persistent dizziness or vertigo at the time of the examination at the emergency department

Exclusion criteria

Having 5 or more prior episodes similar in quality, intensity, and duration to the current symptoms, with at least one episode more than a year prior and one within the past year
Having frank stroke-like symptoms or signs, such as hemiparesis, facial asymmetry, dysarthria, dysphasia, ataxia, gaze palsy
Consciousness disturbance, Glasgow coma scale < 13
Severe dementia
Recent stroke within 3 months
Dizziness or vertigo thought to be the result of head injury, hypotension, medication/drug intoxication, hypoglycemia, electrolyte imbalance, anemia, hepatic encephalopathy, hydrocephalus, etc
Concomitant head or neck trauma
Severe degenerative cervical spondylosis
Having contraindications to magnetic resonance imaging examination