Validation of a Prediction Model for Inadequate Bowel Preparation

General Hospital of Northern Theater Command of Chinese People's Liberation Army

Status: Completed

Conditions: Colonoscopy; Bowel Preparation

Treatments: Procedure: Bowel preparation before colonoscopy

Study type: Observational

Funder types: Other

Identifiers

NCT06438237

V-PMIBP

Details and patient eligibility

About

We have developed a novel inadequate bowel preparation prediction model based on a systematic review and meta-analysis. The goal of this multicenter observational study is to validate the accuracy of this model.

Full description

The primary outcome is quality of bowel preparation. The secondary outcomes include polyp/adenoma detection rate, willingness of undergoing colonoscopy again and adverse events.

Enrollment: 2,360 patients

Sex: All

Ages: 18 to 94 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. adult patients (age is ≥18 years old);
2. patients undergoing colonoscopy;
3. written informed consent.

Exclusion criteria

1. patients undergoing emergent colonoscopy;
2. patients with major psychiatric disorders;
3. pregnant or breast feeding patients;
4. patients with contraindications for colonoscopy (e.g., heart failure, renal insufficiency);
5. patients suspected to have intestinal obstruction, stenosis or perforation;
6. poor compliance with the bowel preparation protocol (poor compliance is indicated if the dose of medication was < 75% of the prescribed dose;
7. incomplete colonoscopy because of other circumstances apart from inadequate cleansing
8. patients previously enrolled in this study.

Trial design

2,360 participants in 4 patient groups

Patients undergoing colonoscopy in General Hospital of Northern Theater Command

Description:

Patients were informed to eat semi-liquid and non-slag diet for breakfast and lunch and full-liquid diet for dinner on the day before colonoscopy, and be fasting on the day of colonoscopy. A split-dose 3 L PEG regimen was used for all patients.

Treatment:

Procedure: Bowel preparation before colonoscopy

Patients undergoing colonoscopy in First Affiliated Hospital of China Medical University

Description:

Patients were informed to eat semi-liquid and non-slag diet for breakfast and lunch and full-liquid diet for dinner on the day before colonoscopy, and be fasting on the day of colonoscopy. A split-dose 2 L PEG regimen was used for all patients.

Treatment:

Procedure: Bowel preparation before colonoscopy

Inpatients undergoing colonoscopy in Second Affiliated Hospital of Army Medical University

Description:

We retrospectively collect data of inpatients undergoing colonoscopy. Patients were informed to eat semi-liquid and non-slag diet for breakfast and lunch and full-liquid diet for dinner on the day before colonoscopy, and be fasting on the day of colonoscopy. A full-dose 3 L PEG regimen was used for all patients.

Treatment:

Procedure: Bowel preparation before colonoscopy

Patients undergoing colonoscopy in No. 960 Hospital

Description:

Patients were informed to eat semi-liquid and non-slag diet for breakfast and lunch and full-liquid diet for dinner on the day before colonoscopy, and be fasting on the day of colonoscopy. Split-dose 3 L PEG, sodium phosphate or sodium picosulfate regimen were used according to the doctor's advice.

Treatment:

Procedure: Bowel preparation before colonoscopy