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Validation of DRAGON Versus a Simplified DRAGON/Machine Learning

E

East Limburg Hospital

Status

Unknown

Conditions

Stroke, Acute

Study type

Observational

Funder types

Other

Identifiers

Details and patient eligibility

About

The CT-DRAGON score can predict long-term functional outcome after acute stroke treated by thrombolysis. However, implementation in clinical practice is hampered by a lack of validation in the broad spectrum of stroke patients undergoing thrombectomy, whether or not in combination with thrombolysis or conservative treatment. Furthermore, the CT-DRAGON score considers multiple items, which are not always readily available in every setting. This study aims to investigate whether either a simplified version of the CT-DRAGON score with only three clinical items or a machine learning technique could be as powerful and more feasible.

Full description

The investigators aim to validate the CT-DRAGON score in all ischaemic stroke localisations and for all treatment options, including a conservative treatment policy. The predictability will then be compared with on the one hand simplified prognostic models that include only a selective set of highly predictive parameters that have already been described in the literature, such as patient age, National Institutes of Health Stroke Scale (NIHSS) and pre-stroke modified Rankin Scale (mRS). On the other hand, machine learning techniques, that incorporate a large set of variables and have recently shown some promising results, will also be applied to predict long-term outcome after ischaemic stroke.

Enrollment

700 estimated patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

  • all patients diagnosed with a stroke

Exclusion criteria

Trial design

700 participants in 1 patient group

Stroke patients
Description:
All patients diagnosed with a stroke are collected in the database.

Trial contacts and locations

1

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Central trial contact

Elly Vandermeulen, PhD; Dieter Mesotten, MD PhD

Data sourced from clinicaltrials.gov

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