Validation of Kinocardiography, New Technology for Cardiac Linear and Torsional Contractility Measurement, to Assess Heart Failure Patient With Low Ejection Fraction

CHU Brugmann University Hospital

Status: Completed

Conditions: Impaired Left Ventricular Ejection Fraction

Treatments: Device: Kinocardiography

Study type: Interventional

Funder types: Other

Identifiers

NCT03157115

CHUB-Kino-HFrEF

Details and patient eligibility

About

Measuring cardiac contractility is commonly realized with gold standard echocardiography or MRI. Portable devices to measure this contractility are not available as for rhythm and electric function assessment. The new Kinocardiography technology could provide a non invasive and portable tool to measure contractility.

This device records the electric and mechanic function of the heart simultaneously. With electrodes and adequate electronics, ECG is recorded. 6 degrees of freedom accelerometers are also included in the device to measure the micro accelerations of the body at the body surface when the device is placed on the skin. Using physics principles and adequate calibration, those accelerations allow the investigators to calculate parameters such as kinetics energies related to cardiac contractility. Kinocardiography is a non invasive and portable technology.

Enrollment: 130 patients

Sex: All

Ages: 20 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Control group: Left Ventricle Ejection Fraction ≥ 50 %
• Heart failure patients: Left Ventricle Ejection Fraction < 50 %

Exclusion criteria

• Intracardiac devices and arrhythmia at the time of assessment
• Participates in other clinical study or trial.

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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130 participants in 2 patient groups

Impaired left ventricular ejection fraction

Experimental group

Description:

Patients with reduced left ventricular ejection fraction (\< 50 %)

Treatment:

Device: Kinocardiography

Control

Active Comparator group

Description:

Patients with a normal left ventricular ejection fraction (≥ 50 %), without heart failure. The patients from the reduced left ventricular ejection fraction group will be matched with patients from the control group for sex, age, BMI and cardiovascular treatment.

Treatment:

Device: Kinocardiography