Validation of Pre-clinical Nano-Based Analgesics in Cells From Human Dorsal Root Ganglia

M.D. Anderson Cancer Center

Status: Enrolling

Conditions: Spinal Cord Neoplasm

Treatments: Procedure: Biospecimen Collection

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT04533919

2020-0526

NCI-2020-05249 (Registry Identifier)

Details and patient eligibility

About

This study investigates the pre-clinical nano-based analgesics in cells from human dorsal root ganglia (clusters of neurons). Collecting these neurons may help future research related to safe and effective pain treatment.

Full description

PRIMARY OBJECTIVE:

I. To identify translational mechanisms and therapeutics for neuropathic pain, a type of chronic pain that can arise due to injured nerves.

OUTLINE:

Patients' leftover dorsal root ganglia samples are collected during standard of care surgery.

Enrollment: 8 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

---All patients undergoing surgery to resect spinal tumors

Exclusion criteria

---None

Trial design

8 participants in 1 patient group

Basic science (dorsal root ganglia collection)

Description:

Patients' leftover dorsal root ganglia samples are collected during standard of care surgery.

Treatment:

Procedure: Biospecimen Collection