Validation of the Two-minute Walk Test and the Ten-meter Walk Test in Individuals With Cancer (2MWTOnco)

Aline Reinmann

Status

Completed

Conditions

Cancer

Treatments

Diagnostic Test: One leg stance test

Diagnostic Test: 6-minute walking test

Diagnostic Test: 2-minute walking test

Diagnostic Test: 10-meter walk test

Study type

Observational

Funder types

Other

Identifiers

NCT04750148

2020-00126

Details and patient eligibility

About

The aim of this study is to assess the feasibility and the validity of the 2-minute walk test (2MWT) and the 10-meter walk test (10MeWT) compared to the 6-minute walk test (6MWT) for subjects with onco-hematological disease.

Full description

Cancer and its treatments have an impact on the body as a whole. The analysis of the subject's physical capacity is essential to know the basic level of the subject pre-treatment, to evaluate progress following rehabilitation, to set goals to prevent decline in physical capacity or to evaluate changes in physical capacity at different stages of survival. The 6-minute walk test (6MWT) is frequently used in the clinic to assess the physical capacity of the subject in oncology. A variant of the 6MWT exists and has been little studied in an oncological context: the 2-minute walk test (2MWT). The 2MWT is performed in the same way as the 6MWT: the same instructions and the same test procedure. It offers the advantage of being less tiring for the test subjects and saves clinicians time. The 2MWT has been validated in the past for people with COPD or after cardiac surgery. To our knowledge, it has not been validated for cancer patients.

The 10-meter walk test (10MeWT) is frequently used in practice to assess patients' functional capacity. It would be another way to assess the walking ability with a short test.

However, the relationship between the 2MWT, 6MWT and 10MeWT in an oncological context remain unclear.

Enrollment

56 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Have an onco-hematologic disease
Have medical authorization from the patient's oncologist authorizing gait tests
Participate in the HUG rehabilitation program
Be able to give consent by signature
To be of legal age
Do not present pain when walking more than 2/10
Be able to walk with or without technical aids for a period of 6 minutes (as per patient's statement)

Exclusion criteria

Suffer from heart problems
Bone metastases at risk of fracture
Osteoporosis at high risk of fracture
Unbalanced Hypertension (hypertension)
Not being able to carry out the walk tests in their entirety
Not being able to perform the gait tests for reasons related to the side effects of the treatments (anemia, undernutrition, vomiting, severe fatigue, risk of thrombocytopenia, pain).
Not being able to carry out the walking test because of a lack of understanding of the instructions or because of psychological problems.