Validation of Vital Signs and Symptoms for the Diagnosis of Serious Infections in Children in the Paediatric A&E. (ERNIE3)

Catholic University (KU) of Leuven

Status: Completed

Conditions: Meningitis; Urinary Tract Infections; Gastroenteritis; Community-Acquired Infections; Respiratory Tract Infections; Sepsis

Study type: Observational

Funder types: Other

Identifiers

NCT01396798

S52996

Details and patient eligibility

About

Validation of Vital Signs and Symptoms for the Diagnosis of Serious Infections in Acutely Ill Children in a High Prevalent Setting: The Paediatric Accidents & Emergencies through prospective observational data collection concerning specific items from the clinical and technical examination in diagnosing serious infections, such as meningitis, sepsis, pneumonia, pyelonephritis, bronchiolitis with hypoxia. Eventually we will attempt to validate a vital signs and symptoms rule derived from multiple low to high prevalent settings of acutely ill children.

Enrollment: 1,500 patients

Sex: All

Ages: 1 month to 16 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Children aged 1 month to 16 years
• Acute illness episode of maximum 5 days

Exclusion criteria

• recent trauma
• neurological conditions
• intoxication
• psychiatric of behavioural disorders without a somatic cause
• acute exacerbation of a chronic condition (asthma, known immunodeficiency, diabetes, cystic fibrosis, etc)

Trial design

1,500 participants in 1 patient group

Children with an acute illness

Description:

Children aged 1 month to 16 years of age, which attend the A\&E department of UZLeuven with an acute illness episode of maximum 5 days.