Validation the Artificial Intelligence System for Automatic Evaluation of the Extent of Intestinal Metaplasia

Shandong University

Status

Completed

Conditions

Artificial Intelligence

Endoscopy

Intestinal Metaplasia of Gastric Mucosa

Treatments

Diagnostic Test: The diagnosis of Artificial Intelligence and endosopists

Study type

Observational

Funder types

Other

Identifiers

NCT05464108

2022SDU-QILU-111

Details and patient eligibility

About

The operative link on gastric intestinal metaplasia assessment (OLGIM) staging systems using biopsy specimens were commonly used for histological assessment of gastric cancer risk. But its clinical application is limited for at least biopsy samples. The endoscopic grading system (EGGIM) has been shown a significant correlation with the OLGIM. The investigators designed a computer-aided diagnosis program using deep neural network to automatically evaluate the extent of IM and calculate the EGGIM scores in endoscopy examination. This study is aimed at exploring the relevance of the EGGIM scores automatically evaluated by Artificial Intelligence and OLGIM scores.

Full description

Gastric intestinal metaplasia(GIM) is an important stage in the gastric cancer(GC). The operative link on gastric intestinal metaplasia assessment (OLGIM) staging systems using biopsy specimens were commonly used for histological assessment of gastric cancer risk. However, its need to take at least 4 biopsies is not clinically feasible. The endoscopic grading system (EGGIM) has been shown a significant correlation with the OLGIM. An EGGIM score of 5 was the best cut off value for identifying OLGIM stage III/IV patients. The investigators have designed a computer-aided diagnosis program using deep neural network to automatically evaluate the extent of IM and calculate the EGGIM scores in endoscopy examination. This study is aimed at exploring the relevance of the EGGIM scores automatically evaluated by Artificial Intelligence and OLGIM scores.

Enrollment

1,080 patients

Sex

All

Ages

40 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

patients aged 40-75 years who undergo the IEE examination

Exclusion criteria

patients with severe cardiac, cerebral, pulmonary or renal dysfunction or psychiatric
disorders who cannot participate in gastroscopy
patients with previous surgical procedures on the stomach
patients with contraindications to biopsy
patients who refuse to sign the informed consent form