Validity of Mediastinal Blood Pool SUV Ratio

Assiut University

Status: Unknown

Conditions: Validity of Blood Pool SUV Ratio in Identification of Malignancy in Case of Diseased Liver

Treatments: Radiation: F18 FDG

Study type: Observational

Funder types: Other

Identifiers

NCT05258045

PET/CT in malignancy

Details and patient eligibility

About

-Validity of blood pool SUV ratio in identification of malignancy in case of diseased liver.

Full description

PET/CT is the functional imaging tool that can measure increased glucose metabolism in cancer tissues by using flourine 18 FDG which is FDA approved and used routinely in identification of malignant lesions , staging and restaging of many malignancy like lymphoma, breast cancer, lung cancer and cancer colon.

In clinical routine, SUV is often used to determine the glucose metabolism in tumours by 18F-FDG PET/CT. And can be further normalised to SUVs in reference regions resulting in a SUV ratio (SUV ratio).in routine work SUV of the lesion is normalised to SUV of the liver , but this not used if the liver is diseased like as liver cirrhosis or liver metastases , so SUV ratio of lesion to mediastinal blood pool and SUV ratio of the lesion to liver will be measured in correlation to pathology to assess validity of SUV of mediastinal blood pool.

Enrollment: 55 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• This study will include cancer pt who did PET/CT scan who presented to nuclear medicine unit during the period from 2021 until the end of the study.

Exclusion criteria

• Severely ill patient
• Pt with glucose level above 200

Trial design

55 participants in 1 patient group

SUV ratio of mediastinal blood pool to the lesion and SUV ratio of liver to lesion

Description:

Avidity of SUV of blood pool

Treatment:

Radiation: F18 FDG