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Valsalva Manœuvre in the Diagnosis of Left Ventricular Failure in Chronic Obstructive Pulmonary Disease Exacerbation

U

University of Monastir

Status

Completed

Conditions

Acute Heart Failure
COPD Exacerbation

Treatments

Other: Valsalva maneuver

Study type

Interventional

Funder types

Other

Identifiers

NCT01619540
Valsalva

Details and patient eligibility

About

Left ventricular failure (LVF) is a common cause of acute exacerbation of chronic obstructive pulmonary disease (AECOPD).

This association is frequently underestimated with regard to the difficulty of clinical diagnosis .

The investigators expect that Valsalva Maneuver (VM) could be useful in this issue.

Enrollment

150 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria

  • We included in this group, patients with a history (previous history) of COPD who consulted the emergency room for an exacerbation of COPD defined by a respiratory rate> 25c/min and a pH <7.35 and a PaCO2 >6 KPa.
  • This group is also divided into two groups according to clinical expert assessment and the BNP value: Group1 : BNP> 400pg/ml, Group2 : BNP <400PG / ml

Exclusion Criteria:

  • We excluded from this study patients with Prominent cardiac arrest
  • Rhythm disorders including severe tachycardia arrhythmia
  • Auricular fibrillation
  • Hemodynamic instability requiring the use of vasoactive drugs and a contre indications of non invasive ventilation such us consciousness disorders with a Glasgow score <12/15,a swallowing disorder
  • A significant bronchial obstruction ,the upper airway obstruction , in upper gastrointestinal bleeding in progress, an extreme obesity and Cirrhosis or cancer.
  • We are also excluded patients who did not cooperate and those who refused the study.

Trial design

Primary purpose

Diagnostic

Allocation

Non-Randomized

Interventional model

Single Group Assignment

Masking

Single Blind

150 participants in 2 patient groups

acute heart failure
Other group
Description:
control arm
Treatment:
Other: Valsalva maneuver
COPD exacerbation
Experimental group
Description:
COPD exacerbation
Treatment:
Other: Valsalva maneuver

Trial contacts and locations

4

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Data sourced from clinicaltrials.gov

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