Value of Additional Corpus Biopsy for Diagnosis of H Pylori in Atrophic Gastritis. Prospective Non-randomized Study

Mansoura University

Status: Unknown

Conditions: Helicobacter Pylori; CORPUS BIOPSIES; Gastric Antrum

Treatments: Other: ENDOSCOPIC GASTRIC BIOPSIES FROM ANTRUM AND BODY

Study type: Interventional

Funder types: Other

Identifiers

NCT02675010

H1

Details and patient eligibility

About

There are controversies about the best sites -biopsy based -tests for H pylori associated gastritis. The study is designed to evaluate the optimal site of gastric mucosal biopsy for identification of Helicobacter pylori, especially in case of gastric atrophy and/or intestinal metaplasia.

Full description

. The study is designed to evaluate the optimal site of gastric mucosal biopsy for identification of Helicobacter pylori, especially in case of gastric atrophy and/or intestinal metaplasia. 400 patients with dyspepsia are planned to be enrolled in this study. in addition to the routine antral biospy, corpus biospies are taken to evaluate the optimal site of gastric mucosal biopsy for identification of Helicobacter pylori, especially in case of gastric atrophy and/or intestinal metaplasia.

Enrollment: 400 estimated patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients included in this study are those with peptic ulcer disease, previous upper gastrointestinal surgery, a known or a suspected past history of H.pylori eradication therapy, a personal or first-degree family history of gastric cancer

Exclusion criteria

• those having received antibiotic or proton pump inhibitor treatment one month beforehand

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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400 participants in 1 patient group

ENDOSCOPIC GASTRIC BIOPSIES

Other group

Description:

ENDOSCOPIC BIOPSEIS TAKEN FROM BOTH ANTRUM AND CORPUS FOR H PYLORI DETECTION

Treatment:

Other: ENDOSCOPIC GASTRIC BIOPSIES FROM ANTRUM AND BODY