Value of Genetic Counseling and Testing for Patients Who Would Like to Know More About Their Personal Risk of AMD

Utah System of Higher Education (USHE) logo

Utah System of Higher Education (USHE)

Status

Completed

Conditions

Choroidal Neovascularization
Genetic Counseling
Age-Related Macular Degeneration

Treatments

Behavioral: Late disclosure
Behavioral: Early disclosure

Study type

Interventional

Funder types

Other

Identifiers

NCT03024424
IRB 60413

Details and patient eligibility

About

The goals of this study are: To assess the impact of genetic testing based on how it alters behaviors, to assess the utility of serum biomarker measurement in combination with genetic testing, to assess the utility of genetic counseling in personal analysis of risk for age-related macular degeneration (AMD), and to assess the impact of presymptomatic genetic testing for choroidal neovascularization (CNV).

Enrollment

16 patients

Sex

All

Ages

18 to 64 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Caucasian (this particular genetic test is only validated in Caucasians) Participants can have a positive family history of AMD but this is not necessary.

Exclusion criteria

  • Individuals with a personal history of AMD are not eligible. Non-caucasian individuals are not eligible. Employees of the Moran Eye Center are not eligible.
  • Individuals with a personal history of previous AMD genetic risk testing are not eligible.
  • Individuals with a major psychiatric disorder

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Triple Blind

16 participants in 2 patient groups

Early disclosure
Experimental group
Description:
Early disclosure group receives results of genetic testing at Week 4
Treatment:
Behavioral: Early disclosure
Late disclosure
Active Comparator group
Description:
Late disclosure group receives results of genetic testing at final study visit (Month 12)
Treatment:
Behavioral: Late disclosure

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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