Value of PET/CT Imaging in the Diagnosis of Permanent Central Venous Catheters Infection

Lausanne University Hospital (CHUV)

Status: Completed

Conditions: Infection

Study type: Observational

Funder types: Other

Identifiers

NCT01434797

89/11

Details and patient eligibility

About

The study hypothesis is that F-18-FDG PET/CT and microcalorimetry might have a diagnostic value in the detection of permanent central venous catheters (PCVC) infection when conventional means of PCVC infection detection are non-conclusive.

Full description

Permanent central venous catheters are frequently infected and therefore need surgical removal. When a clear diagnostic for infection cannot be defined, catheter removal might be at risk for the patient, for the therapeutic follow-up and in terms of costs. PET/CT and microcalorimetry might help giving conclusive diagnostic of catheter infection.

Enrollment: 11 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with confirmed catheter infection requiring surgical removal
• patients with probable catheter infection requiring surgical removal
• patients with planned removal of uninfected catheter
• ≥18years old

Exclusion criteria

• extreme claustrophobia
• pregnancy and breastfeeding
• severe septicemia

Trial design

11 participants in 3 patient groups

Confirmed CVCP infection before removal

Description:

Patients with permanent central venous catheter infection confirmed by conventional method

Presumed CPVP infection before removal

Description:

Patients with probable permanent central venous catheter infection (standard methods for infection detection not conclusive)

Uninfected CVCP before removal

Description:

Patients with planned permanent central venous catheter removal (no infection)