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Value of Pulse Pressure Variations and Corrected Flow Time in Esophageal Doppler as a Predictor of Fluid Responsiveness in Prone Position During Spinal Surgery

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Yonsei University

Status

Completed

Conditions

Elective Posterior Lumbar Spinal Fusion

Treatments

Device: 2. philips Intelivue MP70 monitors
Device: 1.Esophageal doppler monitor

Study type

Interventional

Funder types

Other

Identifiers

NCT01646359
1-2010-0046

Details and patient eligibility

About

In patients under mechanical ventilation, Usefulness of dynamic indices based on the heart-lung interactions for guiding volume resuscitation has been well validated. Recently, validity of pulse pressure variation (PPV) has been also reported to predict fluid responsiveness. Oesophageal Doppler (OED) allows continuous monitoring of several important hemodynamic variables. Of the OED variables, corrected flow time (FTc) has been evaluated and used as a preload index, and has been reported to predict fluid responsiveness. Prone position caused physiologic and hemodynamic changes and influenced the predictability and cut-off values of SVV and PPV for fluid responsiveness. In this prospective controlled study, the investigators evaluated the validity of PPV and FTc as predictors for fluid responsiveness in supine and prone position in patients undergoing posterior lumbar spinal fusion

Enrollment

45 patients

Sex

All

Ages

21 to 69 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • patients undergoing elective spine surgery
  • age : > 20 and < 70, 3. Patients expecting intraoperative blood loss more than 10% of estimated blood volume

Exclusion criteria

  • arrhythmias
  • BMI > 30 kg/m2
  • valvular heart disease
  • left ventricular ejection fraction < 50%
  • history of lung disease
  • pregnancy
  • foreigner
  • contraindications to esophageal doppler monitoring probe insertion (i.e. oesophageal stent, carcinoma of the oesophagus or pharynx, previous oesophageal surgery, oesophageal stricture, oesophageal varices, pharyngeal pouch, intra-aortic balloon pump, coarctation of the aorta, and severe coagulopathy)

Trial design

Primary purpose

Diagnostic

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

45 participants in 1 patient group

corrected flow time
Experimental group
Treatment:
Device: 1.Esophageal doppler monitor
Device: 2. philips Intelivue MP70 monitors

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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