Vancomycin-Associated Acute Kidney Injury: A Cross-Sectional Study From a Multi- Center in China

Peking University

Status: Unknown

Conditions: Vancomycin; Staphylococcal Infections; Adverse Effect; Acute Kidney Injury; Cross-sectional Study

Treatments: Drug: Vancomycin

Study type: Observational

Funder types: Other

Identifiers

NCT03456544

20180122

Details and patient eligibility

About

The objective of this study was to investigate the current situation of vancomycin (VAN)-associated acute kidney injury (VA-AKI) in China and identify the risk factors for VA-AKI, as well as to comprehensively examine the risk related to concurrent drug use. Further, the investigators assessed the outcomes of patients who developed VA-AKI and the risk factors for these outcomes. Finally, the investigators aimed to provide suggestions for improving the prevention and treatment of VA-AKI in China.

Enrollment: 10,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Using Vancomycin
• ≥18 years old

Exclusion criteria

• Medical records were incomplete
• Had been diagnosed with stage 5 CKD or were regularly receiving dialysis
• SCr were not being adequately monitored to detect the development of AKI
• Had undergone nephrectomy

Trial design

10,000 participants in 2 patient groups

VAN-AKI

Description:

Patients who had vancomycin associated acute kidney injury.

Treatment:

Drug: Vancomycin

None VAN-AKI

Description:

Patients who didn't have vancomycin associated acute kidney injury.