Variable-length Cognitive Processing Therapy for Combat-Related PTSD

Duke University

Status: Completed

Conditions: Posttraumatic Stress Disorder

Treatments: Behavioral: Cognitive Processing Therapy-Cognitive Only

Study type: Interventional

Funder types: Other

Identifiers

NCT02313818

W81XWH-13-2-0012 (Other Identifier)

Pro00062853

Details and patient eligibility

About

The primary goal of this study is to improve the overall efficacy of cognitive processing therapy-cognitive-only version (CPT-C) in a sample of 130 active-duty service members through a variable length treatment.

Full description

The primary goal of this study is to improve the overall efficacy of cognitive processing therapy-cognitive-only version (CPT-C) in a sample of 130 active-duty service members through a variable length treatment. The study seeks to determine if some service members would benefit from a longer or shorter dose of treatment (4-24 sessions), and to identify which individuals are likely to require more, less, or the standard number of treatment sessions to reach good end-state functioning. Predictors of length of therapy and treatment outcome will be examined. Specifically, we will evaluate factors related to internalizing/externalizing traits, cognitive flexibility, inability to inhibit dysfunctional cognitions, and readiness to change as they are related to the number of treatment sessions required to treat patients to the point of good end-state functioning. Additional outcomes including alcohol use, psychosocial functioning, physical health, and sleep also will be evaluated.

Enrollment: 130 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult male and female combat veterans who deployed in support of combat operations following 9/11
• Diagnosis of PTSD determined by a Clinician-Administered Posttraumatic Stress Scale (CAPS-5)
• Speak and read English

Exclusion criteria

• Current suicide or homicide risk meriting crisis intervention.
• Active psychosis.
• Moderate to severe brain damage (as determined by the inability to comprehend the baseline screening questionnaires).
• Local availability of fewer than 5 months
• Late-phase Med Board status, awaiting percentages
• Undergoing a chapter

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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130 participants in 1 patient group

CPT-C

Experimental group

Description:

Cognitive Processing Therapy-Cognitive Only (CPT-C) conducted twice weekly for 4-24 sessions based on good end state functioning.

Treatment:

Behavioral: Cognitive Processing Therapy-Cognitive Only