"VARIABLE-PSV" Study
Status and phase
Conditions
Treatments
Details and patient eligibility
About
Variable PSV is a new ventilatory mode which delivered a pressure support "variable" from 0 to 100% variation of the set PSV level.This study aimed to compare the ventilatory behavior, sleep quality and gas exchange between VARIABLE (or Noisy)-PSV and "standard" (or fixed)-PSV during the weaning phase of critically ill patients who required mechanical ventilation.
Full description
Twenty patients will be enrolled. They will be ventilated withVARIABLE-PSV and STANDARD-PSV: for 24 h each in a randomized crossover order. The ventilatory parameters, ventilator/patient asynchrony, gas exchange effects, sleep quality and ventilatory comfort produced by the two ventilation modes will be compared. Before randomisation, a sequence of VARIABLE-PSV will be performed with different level of variation setting to better define the future behavior of the patient under this mode during the 24 h of Variable-PSV.
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
- ventilation planned for more than 48 h
- patient alert and calm corresponding to a Richmond Agitation-Sedation Scale (RASS) between -2 and 0
- Age > or equal 18
- Surrogate decision maker's consent
Exclusion criteria
- Clinical instability for any reason.
- Life support withdrawal code
- Patient under tutelage
- Pregnancy
- No French health insurance
Trial design
Primary purpose
Allocation
Interventional model
Masking
20 participants in 2 patient groups
Trial contacts and locations
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Data sourced from clinicaltrials.gov
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