Variations of the Lung Compliance During Extracorporeal Circulation and Post Operative Pulmonary Complications (COMPLI)

Centre Chirurgical Marie Lannelongue

Status: Completed

Conditions: Cardiopulmonary Bypass; Thoracic Surgery

Study type: Observational

Funder types: Other

Identifiers

NCT02654600

P14-37816002/2014-A00702-45

Details and patient eligibility

About

the decrease in thoracopulmonary compliance after cardiac surgery is well known . The investigators hypothesize that the major factor determining pulmonary outcome after cardiac surgery is the alteration of pulmonary compliance during cardiopulmonary bypass(CBP) and that this alteration is due to CBP itself through pulmonary blood emptying.

Full description

compliance is the compliance calculate when thorax is closed, the pulmonary compliance is the compliance calculated when thorax is opened After operation chest X-ray are daily done and blood samples as needed. Were recorded death, time of extubation,duration of non invasive ventilation,of Intensive Care Unit stay and of total hospital stay, troponin peak, lactates, blood gases, ionogram and count.Variations of compliance is analyzed through one factor paired Anova or Wilcoxon paired test. Decrease of compliance and respiratory complications are analyzed through binomial logistic regression.

Enrollment: 60 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• scheduled for standard aortic
• mitral or coronary surgery

Exclusion criteria

• emergency operation
• no complete preoperative echocardiography
• surgery needing multiple table position changes
• unstable cardiac or respiratory condition
• difficult patient needing multiple care and/or special attention