Varicocelectomy: Can Sex-hormones Predict Improvements in Semen Quality?

Copenhagen University Hospital at Herlev

Status: Terminated

Conditions: Semen Quality; Infertility; Varicocele

Treatments: Procedure: Hormone and semen measurements before varicocelectomy

Study type: Interventional

Funder types: Other

Identifiers

NCT01296230

H-2-2010-067

Details and patient eligibility

About

The purpose of this study is to determine if the pre-operative levels of sex-hormones can be used to identify the varicocele patients who can expect improvements in their semen parameters following varicocelectomy.

Enrollment: 3 patients

Sex: Male

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Varicocele (grade 1-3) and surgery planned for this condition
• At least 18 years of age

Exclusion criteria

• Fever within 3 months before the first semen sample
• Malformations of the uro-genital tract
• Karyotype other than 46, XY or Y micro deletions
• Endocrine disease
• Chronic disease
• Medications which reduce semen quality
• Epididymitis within 6 months before surgery

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

3 participants in 1 patient group

Hormone/semen measurements before and after varicocelectomy

Experimental group

Description:

We will measure sex-hormone and semen quality in patients both before and after varicocelectomy. The purpose is to asses if preoperative hormone levels are predictive for who will have improved semen quality after surgery.

Treatment:

Procedure: Hormone and semen measurements before varicocelectomy