Various Strategies to Reduce Acute Post Hemorrhoidectomy Pain: A Comparative Study

Zagazig University

Status: Completed

Conditions: Acute Post Operative Pain

Treatments: Other: the standard analgesic protocol; Drug: light marcaine; Drug: Diclofenac Sodium Gel; Drug: Corticosteroids injection; Drug: ketorolac and light marcaine

Study type: Interventional

Funder types: Other

Identifiers

NCT06307106

#40\14-Jan-2024

Details and patient eligibility

About

Since post hemorrhoidectomy pain is a severe and common post operative symptom so there is a need to find a suitable method for reducing this pain, up to our knowledge, this the first study in ZUH to compare between ketrolac, light Marcaine, corticosteroids and diclofenac sodium injection at surgical site for relieve of post operative pain. This is a randomized controlled comparative prospective clinical trial.

Enrollment: 150 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• both sex.
• age from 18 to 60.

Exclusion criteria

• patient refusal.
• patients with associated ano-rectal diseases such as fissures, fistulas, ano-proctitis, recurrent or thrombosed hemorrhoids and ano-rectal malignancy.
• patients with liver cell failure. patients unfit for surgery according to American Society of Anesthesiologists.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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150 participants in 5 patient groups

group A: ketorolac and light marcaine injection

Experimental group

Treatment:

Drug: ketorolac and light marcaine

group B: light marcaine injection

Experimental group

Treatment:

Drug: light marcaine

group C: corticosteroids injection

Experimental group

Treatment:

Drug: Corticosteroids injection

group D: topical diclofenac sodium

Experimental group

Treatment:

Drug: Diclofenac Sodium Gel

control group

Sham Comparator group

Description:

control group was given the ordinary analgesic protocol without local analgesic application

Treatment:

Other: the standard analgesic protocol