Vascular and Metabolic Effects of Omega-3 Fatty Acids

Gachon University Gil Medical Center

Status and phase: Completed; Phase 4

Conditions: Hypertriglyceridemia

Treatments: Drug: placebo; Drug: omega

Study type: Interventional

Funder types: Other

Identifiers

NCT01660932

GMC-201103

Details and patient eligibility

About

The investigators hypothesize that omega does-dependently improves vascular and insulin resistance.

Enrollment: 176 patients

Sex: All

Ages: 25 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• hypertriglyceridemia

Exclusion criteria

• overt liver disease, chronic renal failure, hypothyroidism, myopathy, uncontrolled diabetes (HbA1c > 9%), severe hypertension, stroke, acute coronary events, coronary revascularization within the preceding 3 months, or alcohol abuse

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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176 participants in 4 patient groups, including a placebo group

placebo

Placebo Comparator group

Description:

placebo

Treatment:

Drug: placebo

omega 1

Active Comparator group

Description:

omega 1 gm

Treatment:

Drug: omega

omega 2

Active Comparator group

Description:

omega 2 gm

Treatment:

Drug: omega

omega 4

Active Comparator group

Description:

omega 4 gm

Treatment:

Drug: omega