Vascular and Periodontal Disease - Microbial, Genetic and Histological Causalities

University of Oslo

Status: Unknown

Conditions: Periodontitis; Vascular Disease

Study type: Observational

Funder types: Other

Identifiers

NCT01358630

08/322b

Details and patient eligibility

About

The purpose of this study is to analyze genetic polymorphisms in genes encoding pro-inflammatory cytokines, and study the genetic predisposition to chronic periodontitis (CP) in combination with atherosclerotic cardiovascular (ACD) and aneurysmal diseases. The investigators will also try to identify oral bacteria in atherosclerotic plaques and aneurysmal walls and thrombus. Histological analyses of atherosclerotic plaques and aneurysmal wall will be performed.

Enrollment: 100 estimated patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients undergoing vascular surgery at Oslo University Hospital, Aker, previously randomly collected patients with periodontitis,

Exclusion criteria

• patients whom undergone antibiotic treatment the past month.
• patients whom undergone periodontal treatment the past 6 months.
• patients with no teeth