Vascular Changes Associated With Endophthalmitis.

Asociación para Evitar la Ceguera en México

Status: Enrolling

Conditions: Endophthalmitis

Treatments: Diagnostic Test: Multimodal imaging findings

Study type: Observational

Funder types: Other

Identifiers

NCT07175311

RE-24-26

Details and patient eligibility

About

This study aims to describe and investigate vascular changes associated with exogenous endophthalmitis, as well as to create a photo library where they are evidenced

Full description

The implementation of multimodal imaging studies during the diagnosis and follow-up of patients with endophthalmitis may help identify, characterize, and differentiate between changes associated with host immune response, drug toxicity, or ischemia, thereby opening the possibility of implementing early treatments that lead to a better final prognosis. It is designed as a Prospective, Longitudinal, Observational, and Descriptive study. The population will be patients of the retina and vitreous service of Asociación para Evitar la Ceguera en México, who have a complete clinical record (age, sex, pathological personal history, non-pathological personal history, heredofamilial history, ophthalmologic history, allergies, medications, ophthalmologic examination with visual acuity, intraocular pressure at each visit), signed informed consent and with a history of exogenous or endogenous endophthalmitis with clear resolution criteria and clear means one week and one month after meeting the resolution criteria to be able to perform fluorescein angiography at both visits.

Enrollment: 71 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients with a history of endophthalmitis Diagnosis of Endophthalmitis
• Clinical symptoms: Pain, decrease in visual acuity, anterior chamber cells and/or vitreous turbidity, corneal edema, conjunctival hyperemia
• Laboratory studies: B-mode USG and or positive culture
• Patients who meet the endophthalmitis resolution criteria of the Mexican Endophthalmitis Study Group
• Patients with previously signed informed consent

Exclusion criteria

• Patients who have not signed the informed consent
• Patients under 18 years.
• Patients with endophthalmitis who do not meet the resolution criteria of the Mexican Endophthalmitis Study Group

Trial design