Vascular Effects of Sertraline in Heart Failure

Yale University

Status: Terminated

Conditions: Depression; Heart Failure

Treatments: Drug: sertraline

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT00585455

0410027131

Details and patient eligibility

About

To determine the effects of chronic sertraline treatment on brachial artery flow-mediated dilation in patients with chronic heart failure and depression

Enrollment: 4 patients

Sex: All

Ages: 21+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Chronic heart failure with LVEF<40%, age >21 years
• Depression requiring medical treatment with sertraline

Exclusion criteria

• Known intolerance of sertraline

Trial design

4 participants in 1 patient group

A

Description:

Chronic heart failure patients with concomitant depression

Treatment:

Drug: sertraline