Vascular Function on the First Day After Cardiac Surgery

Norwegian University of Science and Technology

Status: Completed

Conditions: Coronary Artery Disease

Study type: Observational

Funder types: Other

Identifiers

NCT02001090

REK nr 2013/1758

Details and patient eligibility

About

This study examines the flow mediated dilation (FMD) of the brachial artery before and after cardiac surgery. FMD is measured with ultrasound technique. Increased flow is achieved trough obstructing blood flow with a cuff around the forearm for five minutes. FMD is measured before surgery and on the first morning after the operation.

Enrollment: 25 patients

Sex: All

Ages: 30+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• admitted for coronary artery bypass surgery

Exclusion criteria

• Ongoing treatment with nitrates or RAAS inhibiting drugs
• unstable coronary syndrome
• unstable circulation/shock
• renal failure
• hepatic failure
• autoimmune or inflammatory disease
• untreated hypertension.

Trial design

25 participants in 1 patient group

CABG patients

Description:

Patients undergoing cardiac surgery for coronary artery disease with the use of heart-lung machine in St Olavs Hospital Trondheim University Hospital.