Vascular Inflammation Stratified by Body Size Phenotype

Korea University

Status: Completed

Conditions: Obesity; Atherosclerosis; Metabolic Syndrome

Study type: Observational

Funder types: Other

Identifiers

NCT01979068

PET_MONW

Details and patient eligibility

About

• Vascular Inflammation is a key factor in both the pathogenesis and outcome of atherosclerosis. 18FDG-PET is a promising novel tool for identifying and quantifying vascular inflammation within atherosclerotic plaque
• Recently, unique subsets of obese individuals, such as metabolically obese but normal weight (MONW) and metabolically healthy obese (MHO), have been getting an attention
• Therefore, the purpose of this study is to examine the relationship of vascular inflammation,measured by FDG-PET, with various body sized phenotypes

Enrollment: 250 patients

Sex: All

Ages: 20 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy patients for visiting routine medical check in our clinic

Exclusion criteria

• history of CVD (myocardial infarction, unstable angina, stroke, or cardiovascular revascularization)
• stage 2 hypertension (resting blood pressure, ≥160/100 mmHg)
• history of inflammatory conditions that affect the study results
• taking medications that might affect inflammatory status, including steroid and non-steroidal anti-inflammatory drug within 6 months
• or malignancy or severe renal or hepatic disease