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Vascular Responses to High vs Low Repetition Resistance Exercise Training in Young Men

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McMaster University

Status

Completed

Conditions

Weight-Lifting Exercise Program

Treatments

Behavioral: Lower-repetition, heavier-load
Behavioral: Higher-repetition, lighter-load

Study type

Interventional

Funder types

Other

Identifiers

NCT02842593
REB 14-333-1

Details and patient eligibility

About

This study evaluates the effects of two types of resistance exercise training (higher-repetition, lower load vs lower-repetition, higher load vs control) on regional and local measures of arterial stiffness in trained young men.

Enrollment

60 estimated patients

Sex

Male

Ages

18 to 30 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Male
  • Aged 18-30 years old
  • Non-obese (Body mass index less than 30 kg/m2)
  • Non-smoker
  • Healthy based on questionnaire responses
  • Resistance trained (Resistance training > 2 times per week for 2 years, minimum 1 lower body exercise session per week)

Exclusion criteria

  • Allergies to milk proteins (whey or casein)
  • Any acute or chronic illness, cardiac, pulmonary, liver, or kidney abnormalities, uncontrolled hypertension, insulin- or non-insulin dependent diabetes or other metabolic disorders-all ascertained through medical history screening questionnaires
  • Arthritic conditions
  • Individuals who consume any analgesic or anti-inflammatory drug(s), prescription or non- prescription, chronically will be excluded
  • A history of neuromuscular problems
  • Individuals on any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications).

Trial design

Primary purpose

Basic Science

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

60 participants in 2 patient groups

Resistance exercise training
Experimental group
Description:
Whole-body resistance exercise training 4x/week for 12 weeks. Either 'lower-repetition, heavier-load' or 'higher-repetition, lighter-load' intervention.
Treatment:
Behavioral: Lower-repetition, heavier-load
Behavioral: Higher-repetition, lighter-load
Non-exercising control
No Intervention group
Description:
Continue habitual physical activity for 12 weeks.

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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