Vascular Sensitivity to Adrenergic Agonists in Patients With CHF and in Healthy Subjects

Hadassah Medical Center

Status: Unknown

Conditions: Congestive Heart Failure

Study type: Observational

Funder types: Other

Identifiers

NCT00782782

366-28.12.07

Details and patient eligibility

About

Congestive Heart failure (CHF) is asociated with changes in cardiac function and vascular responses. The aim of this study is to characterize these differences. Our hypothesis is, that there are differences in vascular responses between healthy subjects and patients with CHF.

Enrollment: 80 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients with congestive heart failure NYHA I-II
• Stable clinical condition

Exclusion criteria

• Resting systolic blood pressure < 100
• Resting heart rate < 50
• Hypersensitivity to dexmedetomidine, phenylephrine, isoproterenol, terbutaline