Vaso-inotropic Score and ECMO-VA Support in Post-cardiotomy Cardiogenic Shock. (ECMOVIS)

University Hospital Center (CHU) Dijon Bourgogne

Status: Completed

Conditions: EMCO-VA

Treatments: Other: data collection

Study type: Observational

Funder types: Other

Identifiers

NCT05412303

GUINOT 2022

Details and patient eligibility

About

Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a well-established lifesaving treatment for refractory cardiogenic shock, with or without concomitant respiratory failure. VA-ECMO is usually started in presence of refractory low cardiac output syndrome following CPB weaning. Currently, there is no consensus about the best timing for implantation and initiation of VA-ECMO in this setting. Some publications have suggested that VIS score could be used to determine the necessity of VA-ECMO in cardiologic area. It was demonstrated that a VIS score between 20 and 40 may be a cut-off value to discuss the implantation of VA-ECMO. Post cardiotomy shock is a very interesting setting because the timing of cardiogenic shock is known and several bias are more controlled than in medical area.

Based on the well-established ability of VIS Score in predicting mortality, we will investigate the role of the VIS Score as a determinant for early VA-ECMO implantation in patients suffering of post-cardiotomy cardiogenic shock.

Enrollment: 2,769 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age over 18 years
• Cardiac surgery with cardiopulmonary bypass
• Post cardiotomy cardiogenic shock
• ECMO-VA implanted in OR

Exclusion criteria

• LVAD
• Heart transplantation
• Incomplete data in relation to outcomes
• Cardiac arrest

Trial design

2,769 participants in 2 patient groups

With ECMO-VA

Description:

postcardiotomy cardiogenic shosck supported by ECMO-VA

Treatment:

Other: data collection

Without ECMO-VA

Description:

Post cardiotomy cardiogenic shock medically treated (inotrope and vasopressor)

Treatment:

Other: data collection