Vasoactive Hormones and Oxygen Saturation During Apneic Events in Patients With Obstructive Sleep Apnea

Regional Hospital Holstebro

Status: Suspended

Conditions: Obstructive Sleep Apnea

Study type: Observational

Funder types: Other

Identifiers

NCT00438412

MED.RES.HOS.2006.01.PHH

Details and patient eligibility

About

The mechanisms involved in development and maintenance of hypertension in obstructive sleep apnea are not clarified.

We hypothesize that patients with obstructive sleep apnea have an abnormal level of some vasoactive hormones during apneic events during sleep.

Enrollment: 40 estimated patients

Sex: All

Ages: 20 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Patients with Obstructive sleep apnea

Inclusion Criteria:

• Severe obstructive sleep apnea (apnea-hypopnea index > 30)

Exclusion Criteria:

• Drug or alcohol abuse
• Pregnancy
• History or clinical signs of disease in the heart, lungs, brain, liver, kidneys or endocrine organs
• Diabetes

Healthy Controls

Inclusion Criteria:

• Apnea-hypopnea index < 10

Exclusion criteria:

• Drug or alcohol abuse
• Pregnancy
• History or clinical signs of disease in the heart, lungs, brain, liver, kidneys or endocrine organs
• Diabetes