Vasoactive Hormones During the Night in Patients With Obstructive Sleep Apnea and Healthy Controls.

Regional Hospital Holstebro

Status: Completed

Conditions: Healthy; Obstructive Sleep Apnea

Study type: Observational

Funder types: Other

Identifiers

NCT00291993

MED.RES.HOS.2004.01.PHH

Details and patient eligibility

About

Obstructive sleep apnea syndrome is complicated by considerable cardiovascular morbidity and mortality, at least partly due to hypertension. Nocturnal hypoxia, hypercapnia and acidosis stimulate chemoreceptors and presumably increased secretion of vasoactive hormones which might be responsible for hypertension in these patients.

The aim of this study is to measure the secretion of vasoactive hormones at night and to analyse the relationship between vasoactive hormones, oxygen saturation and the blood pressure at night.

Sex: All

Ages: 20 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Male and female Age 20-65 Obstructive sleep apnea

Exclusion criteria

Drug or alcohol abuse Pregnancy or breast feeding Cancer Clinical signs or history of disease in the heart, lungs, kidney or endocrine organs Abnormal laboratory tests Albuminuria or glucosuria Aterial hypertension for healthy subjects