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Vasomotor Symptoms in Post-Hysterectomy Women With Ovarian Conservation

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Northwestern University

Status

Invitation-only

Conditions

Vasomotor Symptoms

Study type

Observational

Funder types

Other

Identifiers

NCT07064850
STU00223626

Details and patient eligibility

About

The purpose of this study is to learn about vasomotor symptoms (such as hot flashes and night sweats) in the short-term period after a hysterectomy.

The main question it aims to answer is: How common and severe are vasomotor symptoms shortly after surgery in people who have had a hysterectomy?

Participants will complete a survey before surgery to assess baseline symptoms, and again 2 weeks after surgery to see if there are any changes.

Full description

Hysterectomies are among the most common surgical procedures for women in the United States, with approximately 600,000 operations performed annually. Traditionally, it has been assumed that retaining one or both ovaries during hysterectomy mitigates the onset and severity of vasomotor symptoms, such as hot flashes and night sweats. However, recent research indicates that even with ovarian conservation, women may experience a higher incidence of persistent vasomotor symptoms compared to those who have not had the surgery. These symptoms can significantly impact quality of life, underscoring the need for comprehensive studies that track the progression of vasomotor symptoms post-hysterectomy. Despite their clinical importance, the precise timeline of symptom onset and the influence of ovarian retention remain poorly understood.

Existing studies on surgical menopause primarily focus on factors such as depression, anxiety, and abdominal pain. No study to date has followed women from the immediate postoperative period through the subsequent months to assess the onset, type, and frequency of vasomotor symptoms. Additionally, research on surgical menopause often lacks detailed information on the diagnostic indications for hysterectomy and fails to differentiate between women who retained both ovaries versus those who retained only one at the time of surgery. This study aims to provide a better understanding of the relationship between the onset and severity of vasomotor symptoms in order to improve postoperative care, guide patient counseling, and develop targeted interventions to mitigate vasomotor symptoms.

Enrollment

20 estimated patients

Sex

Female

Ages

35 to 50 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  1. 35-50 years old
  2. Undergoing hysterectomy with at least one ovary conserved
  3. Ability to provide informed consent

Exclusion criteria

(None specified)

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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