VDR SNPs & 25OHD Correlated With Dyslipidemia

Shenzhen Center for Chronic Disease Control

Status: Completed

Conditions: Dyslipidemias; Single Nucleotide Polymorphism

Treatments: Other: No intervention.

Study type: Observational

Funder types: Other

Identifiers

NCT04707612

QLS2015

Details and patient eligibility

About

The project was aimed to explore the associations of single nucleotide polymorphisms (SNPs) of vitamin D receptor gene with specific circulating lipids in adult Chinese. The circulating 25-hydroxyvitamin D concentration was also tested to explore its interactions with SNPs in the associations.

Enrollment: 1,987 patients

Sex: All

Ages: 20 to 81 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 1. ≥ 20 years old Han Chinese;
• 2. living in Shenzhen for > 2 years;
• 3. free of liver diseases, renal diseases, and any cancers in the past 6 months; and
• 4. not in pregnancy for women.

Exclusion criteria

• 1. had severe organic diseases,
• 2. had acute infection symptoms, allergic diseases, and malignant tumors,
• 3. had a family history of genetic diseases,
• 4. took VD supplements in the past 6 months,
• 5. took medicines to control lipid levels within 12 hours, or
• 6. took diuretics, did strenuous exercise, or overate within 24 hours before the test.