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Vein vs Arterial Grafts for Coronary Artery Bypass Grafting Surgery

R

Region Örebro County

Status

Unknown

Conditions

Angina Pectoris

Treatments

Procedure: NT SVG grafts

Study type

Interventional

Funder types

Other

Identifiers

NCT02158455
NTSVGRA

Details and patient eligibility

About

The investigators have developed a novel technique for saphenous vein graft harvesting for coronary artery bypass grafting (CABG) where the graft is harvested with a pedicle of surrounding tissue. A randomized trial has shown a significantly higher patency rate for vein grafts harvested with this new methode compared to conventional harvesting technique 8.5 years after surgery (90 vs 76 %). In 2004 the investigators started a prospective randomized trial comparing patency between vein grafts harvested with surrounding tissue and radial artery grafts. The result showed that vein grafts harvested with surrounding tissue had a significantly higher patency rate compared to radial artery grafts 3 years after surgery (98 vs 84 %). The present study is a long-term follow-up (8 years) of the patients included in the second randomized trial. The hypothesis is that vein grafts harvested with surrounding tissue have a significantly higher patency rate compared to radial artery grafts 8 years after surgery.

Enrollment

108 patients

Sex

All

Ages

Under 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Three vessel coronary artery disease

Exclusion criteria

  • 65 years or older
  • Elevated creatinine
  • Raynauds disease
  • Vein stripping

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

108 participants in 2 patient groups

NT SVG grafts
Experimental group
Description:
NT SVG randomized for revascularization of left or right coronary territory
Treatment:
Procedure: NT SVG grafts
RA grafts
Active Comparator group
Description:
RA grafts randomized for revascularization of left or right coronary territory
Treatment:
Procedure: NT SVG grafts

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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