VENOUS: A Translational Study of Enterococcal Bacteremia

The University of Texas System (UT)

Status: Enrolling

Conditions: Enterococcal Bacteremia

Study type: Observational

Funder types: Other

Identifiers

NCT04410276

HSC-MS-15-0055

Details and patient eligibility

About

The purpose of this study is to assemble a multicenter prospective cohort of patients with enterococcal bloodstream infections (BSIs) to provide data on outcomes of patients with enterococcal BSIs for sample size calculations for future trials, as well as to characterize enterococcal isolates causing BSIs in order to comprehensively dissect the molecular epidemiology of infecting organisms for future studies.

Enrollment: 1,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Hospitalized patient
• ≥1 positive blood culture with Enterococcus spp. (VRE or VSE) during hospitalization
• bacterial isolate(s) is/are available for further characterization
• Repeat blood culture(s) within 7 days from the first positive culture

Exclusion criteria

• Cultures obtained from patients not admitted to the hospital
• Isolate(s) not available for further studies.

Trial design

1,000 participants in 1 patient group

Patients with enterococcal bloodstream infections

Description:

Adult patients (≥ 18 years of age) with ≥ 1 positive blood cultures with Enterococcus during hospitalization and who have repeat blood culture(s) within 7 days from the first positive culture will be included.