Venous Congestion and Acute Renal Failure in Cardiac Surgery Postoperative (COVD)

University Hospital, Strasbourg, France

Status: Unknown

Conditions: Acute Renal Failure (ARF)

Study type: Observational

Funder types: Other

Identifiers

NCT03013621

6296

Details and patient eligibility

About

Acute renal failure (ARF) is a frequent complication in the postoperative cardiac surgery, and is a major risk factor for mortality in this context.

The right ventricular dysfunction post cardiopulmonary bypass (CPB) is also a common complication, close to 100% if one takes into account the transient dysfunction.

A recent study showed that right ventricular dysfunction and the IRA seemed related, rather on the slope of venous congestion. We wish to study this phenomenon more specifically in particular to offer reliable diagnostic markers of venous congestion.

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age: all major patient
• Gender: both
• Subject has signed an informed consent
• IRA KDIGO stage 1 or urine output <0.5 mL / kg / h for at least 6 hours / elevation creat> 26.5μmol / L
• Patient in sinus rhythm at the time of the ultrasound measurements
• No diuretic since intervention
• Absence of circulatory failure (low doses of catecholamines tolerated)
• Extubated: absence of mechanical ventilation

Exclusion criteria

• Chronic heart failure right
• Chronic renal failure (GFR <60)
• Usual treatment with high dose diuretics (furosemide> 40mg / day)
• Endocarditis
• Emergency surgery (aortic dissection, emergency bypass surgery) / heart surgery D / redux
• Circulatory Support
• ACFA / electro-paced rhythm
• Inability to give informed about information (subject in emergencies, understanding of the subject of difficulty, ...)
• Topic under judicial protection
• Topic guardianship or curatorship
• Pregnancy (women of childbearing age)
• Breastfeeding