Venous Disease Thromboembolic and Amyotrophic Lateral Sclerosis (TESLA)

Regional University Hospital Center (CHRU)

Status: Completed

Conditions: Lateral Amyotrophic Sclerosis; Venous Thrombo-embolic Desease

Study type: Observational

Funder types: Other

Identifiers

NCT04446325

29BRC19.0236

Details and patient eligibility

About

Venous thrombo-embolic (VTE) rates could be high in patients with amyotrophic lateral sclerosis (ALS). Indeed, the rate of VTE in this specific population could be 7-fold higher in this population. Predictiv factors of VTE in patients with ALS are mobility reduction and neurological paralysis. However, to our knowledge, medical littérature is poor concerning VTE and ALS association.

Our first aim is to define annual rate of VTE in ALS population.Then we aim to identify predictiv factors of VTE in this specific population. The studied population is Brest universitary hospital cohort of ALS patient included between 2000 and 2019.

Enrollment: 227 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with amyotrophic lateral sclerosis defined by revised El Escorial score criteria followed in competence centre of Brest Universitary Hospital during 2000 to 2019

Exclusion criteria

• no consent
• other neuro-degenerativ diseases