Venous Thromboembolism in Advanced Lung Cancer (RIVAL)

Guangdong Provincial People's Hospital (Guangdong Provincial Academy of Medical Sciences)

Status

Unknown

Conditions

Lung Neoplasms

Venous Thromboembolism

Treatments

Other: lung cancer

Study type

Observational

Funder types

Other

Identifiers

NCT03581708

No.GDREC 2018009H

Details and patient eligibility

About

This is a prospective observatory clinical study, aiming to establish and validate venous thromboembolism risk model in Chinese advanced non-small cell lung cancer.

Full description

VTE has high incidence in lung cancer and increases the mortality. Appropriate preventive measures contribute to 50% increase of incidence. The investigators are to investigate the VTE in advanced non-small cell lung cancer and delineate the risk factors to establish a VTE risk model system helping clinicians to differentiate VTE high risk population and apply early prevention in order to reduce the incidence of VTE.

Enrollment

1,400 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Age ≥ 18 years at the time of screening.
Eastern Cooperative Oncology Group performance status of ≤ 2.
Written informed consent obtained from the patient.
Histologically and cytologically documented Stage 3B-4 lung cancer (according to Version 8 of the International Association for the Study of Lung Cancer Staging system).
Patients with stage 1 to 3, who undergo radical therapy with disease free survival (DFS) >12 months.
Willingness and ability to comply with scheduled visits and other study procedures.

Exclusion criteria

History of another primary malignancy except for malignancy treated with curative intent with known active disease ≥ 5 years before date of the informed consent.
Without signed informed consent.
Unwillingness or inability to comply with scheduled visits or other study procedures.
Previously diagnosed with VTE before signing informed consent.